God, No!

Penn Jillette draws a sharp line between beliefs preserved by tradition and knowledge anchored in reality and repeatable discovery:

If every trace of any single religion were wiped out and nothing were passed on, it would never be created exactly that way again. There might be some other nonsense in its place, but not that exact nonsense. If all of science were wiped out, it would still be true and someone would find a way to figure it all out again.

• Penn Jillette, "God, No! Signs You May Already Be an Atheist and Other Magical Tales"

As Richard Feynman put it decades earlier:

The test of all knowledge is experiment. Experiment is the sole judge of scientific truth.